Abstract

In this review article, it is emphasized that adopting advanced molecular diagnostics is essential for modern UTI management, offering a more comprehensive, accurate, and rapid approach compared to traditional methods. Standard urine culture’s limitations include low sensitivity and failure to culture certain microorganisms, leading to undiagnosed cases and increased morbidity. Advanced molecular techniques, like multiplex-PCR and pooled antibiotic susceptibility testing have been shown to reduce empiric treatments and negative outcomes significantly. And advanced molecular methods like metagenomics (mNGS) offer comprehensive pathogen detection without prior knowledge of target organisms, improving diagnostic yield. These methods also detect antibiotic resistance genes, aiding in precise treatment strategies and improving patient outcomes. Adopting advanced molecular diagnostics is essential for modern UTI management, offering a more comprehensive, accurate, and rapid approach compared to traditional methods. These technologies are vital in improving patient care and combating antibiotic-resistant infections.

Description

Copyright © 2024 The Author(s): This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted use, distribution, and reproduction in any medium for non-commercial use provided the original author and source are credited.

Publisher

South Asian Research Publication

Date of publication

Summer 6-26-2024

Language

english

Persistent identifier

http://hdl.handle.net/10950/4727

Document Type

Article

Publisher Citation

Rob E. Carpenter (2024). Beyond Standard Urine Culture: Advanced Molecular Testing for Urinary Tract Infections, SAR J Med, 5(3), 80-86.

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