Our research within the department of Cellular and Molecular Biology emphasizes basic and translational science as well as the development of therapeutic interventions. To achieve our scientific goal, we employ the following multi-disciplinary approach: Molecular genetics Cell biology Cellular and molecular imaging Biochemistry Biophysics Immunology Animal model, including KO mouse

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Submissions from 2023

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Bacterial Outer Membrane Vesicles Promote Lung Inflammatory Responses and Macrophage Activation via Multi-Signaling Pathways, Sunhyo Ryu, Kareemah Ni, Chenghao Wang, Ayyanar Sivanantham, Johnathan M. Carnino, Hong-Long Ji, and Yang Jin

Submissions from 2022

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MetaLP: An integrative linear programming method for protein inference in metaproteomics, Shichao Feng, Hong-Long Ji, Huan Wang, Bailu Zhang, Ryan Sterzenbach, Chongle Pan, and Xuan Guo

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Obesity and the Development of Lung Fibrosis, Xia Guo, Christudas Sunil, and Guoqing Qian

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Caveolin-1-Derived Peptide Reduces ER Stress and Enhances Gelatinolytic Activity in IPF Fibroblasts, Satoshi Komatsu, Liang Fan, Steven Idell, Sreerama Shetty, and Mitsuo Ikebe

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Mitochondria-associated myosin 19 processively transports mitochondria on actin tracks in living cells, Osamu Sato, Tsuyoshi Sakai, Young-yeon Choo, Reiko Ikebe, Tomonobu M. Watanabe, and Mitsuo Ikebe

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Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, Jue Wang, Shiva Keshava, Kaushik Das, Richard Kolesnick, Xian-Cheng Jiang, Usha R. Pendurthi, and L. Vijaya Mohan Rao

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Prkg2 regulates alveolar type 2-mediated re-alveolarization, Mo Zhang, Gibran Ali, Satoshi Komatsu, Runzhen Zhao, and Hong-Long Ji

Submissions from 2021

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Protein kinase D promotes airway epithelial barrier dysfunction and permeability through down-regulation of claudin-1, Huachen Gan, Guibo Wang, Qin Hao, Q. Jane Wang, and Hua Tang

Submissions from 2019

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Upregulation of the WNK4 signaling pathway inhibits epithelial sodium channels of mouse tracheal epithelial cells after influenza A infection, Yapeng Hou, Yong Cui, Zhiyu Zhou, Hongfei Liu, Hongfei Zhang, Yan Ding, Hongguang Nie, and Hong-Long Ji

Submissions from 2017

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ENaCs as Both Effectors and Regulators of MiRNAs in Lung Epithelial Development and Regeneration, Yan Ding, Runzhen Zhao, Xiaoli Zhao, Michael A. Matthay, Hong-Guang Nie, and Hong-Long Ji

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Metalloproteinase-9 contributes to endothelial dysfunction in atherosclerosis via protease activated receptor-1, Jon M. Florence, Agnieszka Krupa, Laela M. Booshehri, Timothy C. Allen, and Anna K. Kurdowska

Submissions from 2016

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Potential roles of amiloride-sensitive sodium channels in cancer development, Siguang Xu, Cui Liu, Yana Ma, Hong-Long Ji, and Xiumin Li

Submissions from 2015

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Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response, Agnieszka Krupa, Marek Fol, Bozena R. Dziadek, Ewa Kepka, Dominika Wojciechowska, Anna Brzostek, Agnieszka Torzewska, Jaroslaw Dziadek, Robert P. Baughman, David Griffith, and Anna K. Kurdowska

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Genes regulating epithelial polarity are critical suppressors of esophageal oncogenesis, Xiu-Min Li, Hui Wang, Li-Li Zhu, Run-Zhen Zhao, and Hong-Long Ji

Submissions from 2014

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Role of tissue factor in mycobacterium tuberculosis-induced inflammation and disease pathogenesis, Hema Kothari, Shiva Keshava, Rit Vatsyayan, Nigel Mackman, L. Vijaya Mohan Rao, and Usha R. Pendurthi