Abstract
Objective: To examine the therapeutic potential of stochastic vibrotactile stimulation (SVS) as a complementary non-pharmacological intervention for withdrawal in opioid-exposed newborns.
Study design: A prospective, within-subjects single-center study was conducted in 26 opioid-exposed newborns (>37 weeks; 16 male) hospitalized since birth and treated pharmacologically for Neonatal Abstinence Syndrome. A specially-constructed mattress delivered low-level SVS (30-60Hz, 10±12μm RMS), alternated in 30-min intervals between continuous vibration (ON) and no vibration (OFF) over a 6±8 hr session. Movement activity, heart rate, respiratory rate, axillary temperature and blood-oxygen saturation were calculated separately for ON and OFF.
Results: There was a 35% reduction in movement activity with SVS (p<0.001), with significantly fewer movement periods >30 sec duration for ON than OFF (p = 0.003). Incidents of tachypneic breaths and tachycardic heart beats were each significantly reduced with SVS, whereas incidents of eupneic breaths and eucardic heart beats each significantly increased with SVS (p<0.03). Infants maintained body temperature and arterial-blood oxygen level independent of stimulation condition.
Description
© 2017 Zuzarte et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Publisher
PLOS One
Date of publication
4-2017
Language
english
Persistent identifier
http://hdl.handle.net/10950/4451
Document Type
Article
Recommended Citation
Zuzarte, Ian; Indic, Premananda; Barton, Bruce; Paydarfar, David; Bednarek, Francis; and Bloch-Salisbury, Elisabeth, "Vibrotactile stimulation: A nonpharmacological intervention for opioid-exposed newborns" (2017). Electrical Engineering Faculty Publications and Presentations. Paper 16.
http://hdl.handle.net/10950/4451