Procedures for diagnosis of mammary candidosis, including laboratory confirmation, are not well defined. Lactoferrin present in human milk can inhibit growth of Candida albicans, thereby limiting the ability to detect yeast infections. The inhibitory effect of various lactoferrin concentrations on the growth of C. albicans in whole human milk was studied. The addition of iron to the milk led to a two- to threefold increase in cell counts when milk contained 3.0 mg of lactoferrin/ml and markedly reduced the likelihood of false-negative culture results. This method may provide the necessary objective support needed for diagnosis of mammary candidosis.
This article was originally published in the Journal of Clinical Microbiology.
American Society for Microbiology
Date of publication
Francis, Jimi; Pappagianis, Demosthenes; Heinig, M. Jane; Lonnerdal, Bo; and Dewey, Kathryn G., "Detecting Candida albicans in Human Milk" (2003). Health and Kinesiology Faculty Publications and Presentations. Paper 13.